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Arguable the best doctor games ever produced for the PC (well, Theme Hospital comes close, but that is more of a management game), Life & Death 1 and 2 put you in the role of surgeon who specializes in digestive systems in the first game, and brain surgery in the second. Diagnose patients correctly and perform increasingly difficult more advanced procedures to get promoted. The games are much celebrated for their strong emphasis on realism (not surprisingly, since their designer is a real doctor). The games also boast high educational value as well, since every time you make mistakes you'll be sent to a classroom to learn what you did wrong. And yes, there IS an end to each of these games-- it just takes a lot of patience, dozens of successful surgeries, and steady hands :)
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Life and Death 2: The Brain screenshot
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Life and Death, SimIsle for Windows 95, SimTower